Some email provider accept regular expressions to blacklist additional spam. My blacklist is long and tedious to update, but hey… Emacs org babel can simplify things here.
It's way easier to maintain a blacklist (with no regex) using an org table.
and subsequently use org babel (elisp snippet) to generate the regex.
UPDATE: Tweaked elisp and regex (but not animation) also found John Bokma's post: Blacklisting domains with Postfix.